Natalia Castro, a poisonous maid, suffered a decade of inhuman torture at the hands of the poisonous doctor, enduring a life of agony and experimentation. Until her stepmother found her and forced her into a substitute marriage. However, by fate, she became the only cure for General Silvio Juárez. Thus began her new life in the Juárez mansion. They fell in love with each other, and as the new mistress, no one dared to humiliate her.